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Psychiatric Drugs

May 25, 2005

Much of this data comes from the Massachusetts Department of Mental Health online, plain English psych drug manual (http://www.mass.gov/Eeohhs2/docs/dmh/publications/medication_manual.doc). It's a good guide, but is not fully complete with its side effects.


I.  Anti-Anxiety / Sleep Medication / Minor Tranquilizers

Benzodiazepine Category:

Xanax®
Librium®
Klonopin®
Tranxene®
Valium®
Ativan®

Other:

Buspar®
Sonata®
Ambien®

** These drugs basically give you the feeling of being drunk and are very addictive.

Relatively Common:

Drowsiness,* dizziness, slow reactions.

Less Common:

Problems with memory, slurred speech, poor concentration, poor coordination, muscle weakness, increased anger or agitation.

This medication is considered to be habit forming. Most people will have withdrawal side effects if they stop taking it suddenly. Withdrawal effects may include worsening anxiety, nausea, vomiting, sleep loss, tremors,* low blood pressure, or seizures.*

 
II.  Antidepressants

Serotonin Re-Uptake Inhibitors (SSRIs):

Celexa®
Lexapro®
Prozac®
Luvox®
Paxil®
Zoloft®

Other New Types of Antidepressants:

Remeron®
Serzone®
Desyrel®
Effexor®

** These newer antidepressants allegedly operate by preventing the brain from killing off some of the brain-nerve chemicals that send signals between nerves. This theory is unproven and depression cannot be diagnosed in this manner.

** One gets more of an upper effect from these newer antidepressants.

Risks of This Medication:

The following are some of the possible side effects that may happen while taking this medication:

Relatively Common:

Drowsiness,* dizziness or lightheadedness (especially when getting up suddenly from a lying or sitting position), low blood pressure, constipation, dry mouth, blurry vision, weight gain, upset stomach.

Less Common:

Confusion, difficulty passing urine, unusually fast or uneven heartbeat, decreases in sexual drive or function.

Rare:

Seizures,* liver problems, worsening of glaucoma* (if this were to happen, you would get severe eye pain, and you would need medical help).

** These drugs also cause bizarre acts of violence, such as many of the school shootings around the country.

** Below is the new Black Box warning now on these newer antidepressants' information sheets.

Suicidality in Children and Adolescents

Antidepressants increase the risk of suicidal thinking and behavior (called "suicidality") in children and adolescents with major depressive disorder (MDD) and other psychiatric disorders. In clinical trials in which over 4,000 patients participated, the risk of such suicidality was 4% (compared to 2% on placebo). There were no suicides in these trials. Anyone considering the use of antidepressants in a child or adolescent must balance this risk with the clinical need. Patients started on therapy should be observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescribing clinician.

Risks of This Medication:

The following are some of the possible side effects that may happen while taking this medication.

Relatively Common:

Trouble sleeping, anxiety, nervousness or restlessness, nausea, decreased appetite or weight loss, potential weight gain, decreased sexual arousal or decreased ability to have an orgasm or ejaculation, headache, diarrhea, drowsiness,* unusual dreams.

Less Common:

Tiredness, dizziness, constipation, decreased concentration, fast or uneven heartbeat, dry mouth, stuffy nose, vomiting, tremors,* twitching muscles, sweating, seizures.*

Older Types of Antidepressants:

Elavil®
Ascendin®
Anafranil®
Desipramine
Norpramin®
Sinequan®
Imipramine®
Tofranil®
Pamelor®
Vivactil®
Surmontil®

These are a Different Type of Older Antidepressant:

Nardil®
Parnate®

** These older antidepressants have a tranquilizing effect.

Risks of This Medication:

Relatively Common:

Sedation, drowsiness,* dizziness or lightheadedness (especially when getting up suddenly from a lying or sitting position), low blood pressure, constipation, dry mouth, blurry vision, weight gain, upset stomach, difficulty passing urine, unusually fast or uneven heartbeat, changes in sexual drive and function such as inability to reach orgasm.

Less Common:

Confusion, seizures,* sweating, liver problems, high blood pressure reactions (explained below), chest pain, headache, rash, worsening of glaucoma* (if this were to happen, you would get severe eye pain, and you would need medical help).

 
III.  Antipsychotic Medications

Typical Antipsychotics (Older Drugs):

Thorazine®
Prolixin®
Deconoate®
Haldol®
Loxitane®
Moban®
Trilafon®
Navane®
Stelazine®
Serentil®
Mellaril®

** These drugs are very powerful tranquilizers. The first, thorazine, was developed in 1954 and marketed as "chemical lobotomy" – a replacement for the lobotomy – as it leaves people in a heavily tranquilized drug stupor wherein a person drools, cannot think straight, etc., as if he were lobotomized.

Risks of This Medication:

The following are some of the possible side effects that may happen while taking this medication.

Relatively Common:

Sedation, muscle stiffness, tremors,* slowed muscle movements, muscle spasms, restlessness, dizziness, constipation, dry mouth, blurry vision, weight gain, upset stomach, body heat regulation problems.

Some patients taking these medications may experience trouble staying cool in hot weather. This can be dangerous during heat waves or excessive physical activity.

Less Common:

Stuffy nose, difficulty passing urine, low blood pressure, unusually fast or uneven heartbeat, impotence,* breast enlargement, loss of menstrual cycle, sensitivity to the sun, difficulty swallowing, seizures.*

Tardive Dyskinesia (Late Acting Muscle Movements):

This side effect can happen to people who take an antipsychotic medication for a long time. Usually, it does not appear until after 6 months or more of treatment. It involves uncontrollable and abnormal muscle movements. Often these movements are in your tongue, mouth and face, but they can happen in other parts of your body, like your arms or legs, or even rarely in the muscles that help you breath. You may not notice these movements, although others around you may notice them. You should also understand that these movements might not go away even if the medication is stopped. The risk for this side effect increases the longer you are treated with an antipsychotic medication and the older you are.

Neuroleptic Malignant Syndrome:

This is a rare problem that can happen with any antipsychotic medication. People that get this side effect have a change in the way they act, a fever, muscle stiffness, and changes in their blood pressure and heart rate. Although it is rare and most people recover completely, some people have died from this problem.

Atypical Antipsychotics (Newer Agents):

Abilify®
Clozaril®
Zyprexa®
Seroquel®
Risperidone®
Geodon®

** A new Black Box warning is going on these new, atypical antipsychotics. It will show that these new heavy tranquilizers cause diabetes. This is from creating massive weight gain. It has also been found that these new drugs create almost as much permanent twitching and shaking effects as the older, thorazine-type drugs. This is something the drug companies lied about for years to sell these drugs. Studies have also shown that these drugs, often used on the elderly for dementia (not to help, but to tranquilize them) kill off the elderly at a 60%-70% increase.

** Antipsychotics are psychiatry's most powerful and dangerous drugs. The newer (atypical) antipsychotics make psychiatry and drug companies the most money. They are very expensive and your tax dollars pay for these.

Risks of This Medication:

Relatively Common:

Dizziness, low blood pressure when you stand up quickly, dry mouth, stomach upset, sleepiness, headache, constipation, weight gain, liver test problems (these usually return to normal on their own), increased blood fat levels.

Weight gain may occur on this medication and can be preventable in many cases if the right support and strategies are in place. The cause of weight gain is unknown but may be involved with appetite control, such as not feeling full, leading to more eating. People who gain weight are at risk of developing diabetes (see below) or having problems with fats in their blood that can contribute to heart disease.

Diabetes (trouble with sugar control) may be more of a risk for people who take this medication. Your ethnic background, family history and medical history may also affect your risk of developing diabetes. Please be sure to discuss these risks with your healthcare provider.

Less Common:

Muscle stiffness, tremors,* slowed muscle movements, muscle spasms, restlessness, seizures,* decreased thyroid levels, fast heart beat.

Tardive Dyskinesia (Late Acting Muscle Movements):

This side effect can happen to people that take this kind of antipsychotic medication for a long time. Usually, it does not appear until after 6 months or more of treatment. It involves incontrollable and abnormal muscle movements. These movements may not go away even if the medication is stopped.

 
IV.  Mood Stabilization Medications

Carbatrol®, Tegretol®
Neurontin®
Lamictal®
Lithium
Trileptal®
Topamax®
Depakote®, Depakene®
Calan®

** These drugs dull your emotions, less happy, less sad, etc. These drugs are very different so the side effects differ. With lithium, it attacks the thyroid, liver and kidneys. These drugs generally tranquilize and can cause seizures and many other bad effects.

 
V.  Stimulant Medications:  Attention-Deficit / Hyperactivity Disorders

Psychostimulants (Speed, Emphetamines) :

Dexedrine®
Adderall® (recently banned in Canada for causing heart attacks)

Methylphenidate Derivatives (these are similar to cocaine):

Ritalin®
Concerta® (slow release Ritalin)
Metadate®
Cylert (this is coming off the market after causing a lot of liver damage)

** Amphetamines are used to tranquilize hyperactive kids through heavy doses. CCHR New England surveys of Ritalin snorters (maybe 150 lbs. of weight) show that an adult-aged person starts at 5-10 mgs of the drug while little children (maybe 50 lbs.) start at about 20 mgs and could go up to 60 mg/day. A little of a drug makes you high, more is tranquilizing (like in alcohol for example) and too much is toxic.

Risks of These Medications:

Relatively Common:

Trouble sleeping, loss of appetite, irritability, weight loss, stomach ache, headache, nervousness, restlessness, dizziness.

Less Common:

Fast or pounding heartbeat, increased blood pressure, changes in mood (sad, depressed), unusual muscle movements called tics, changes in growth rate of some children (see special instructions below).

When coming off these amphetamine/cocaine type drugs, a speed crash occurs wherein children can become depressed or suicidal. They can also become psychotically violent from the drugs.

Unusual:

Irregular heartbeat, psychosis.

Other:

Atomoxetine Strattera®

** This is a non-stimulant ADHD drug but we have cases of it making a child psychotic.

Relatively Common:

Stomach pain, headache, vomiting, decreased appetite, cough, nausea, irritability, dizziness, sleepiness.

Less Common:

Sexual difficulties,* increased blood pressure, increased heart rate, urinary retention,* lightheadedness, weight loss, constipation, dry mouth.

Allergic Reaction:

One or a combination of the following symptoms: itching or rash, swelling in face or hands, swelling or tingling in the mouth or throat, chest tightness and/or trouble breathing.

 
VI.  Other Psychoactive or Adjunctive Medications

Symmetrel®
Cogentin®
Artane®

** These drugs are solely used to hide the permanent shaking, twisting and muscular tensing effects of the antipsychotic drugs. People just look better while they are being harmed. They do no real good at all.

Side effects include:

Relatively Common:

Dry mouth, blurred vision, constipation, difficulty passing urine

Less Common:

Drowsiness,* confusion, memory problems, dizziness, unusually fast heartbeat, skin rash.

Rare:

Worsening of glaucoma* (if this were to happen, you would get severe eye pain, and you would need medical help).

For more information, contact:

Citizens Commission on Human Rights New England
1112 Boylston Street, PMB 213
Boston, MA 02215
Phone: 617-927-CCHR
Fax: 617-927-0515
Citizens Commission on Human Rights

FAIR USE NOTICE


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